Epicentre of the Roman Empire and birthplace of the Renaissance, this European virtuoso groans under the weight of its cultural cachet: it’s here that you’ll stand in the presence of Michelangelo’s David and Sistine Chapel frescoes, Botticelli’s Birth of Venus and Primavera and da Vinci’s The Last Supper. In fact, Italy has more Unesco World Heritage cultural sites than any other country on Earth. In few places do art and life intermingle so effortlessly. This may be the land of Dante, Titian and Verdi, but it’s also the home of Prada, Massimo Bottura and Renzo Piano. Italy’s fortes extend beyond its galleries, wardrobes and dining rooms. The country is one of nature’s masterpieces, with extraordinary natural diversity matched by few. From the north’s icy Alps and glacial lakes to the south’s fiery craters and turquoise grottoes, this is a place for doing as well as seeing.